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The Allen Research Group is pursuing diverse research topics in the field of Tissue Engineering and Regenerative Medicine. Our work includes areas related to cell and molecular biology, cell-material interactions, material science and engineering, and mechanobiology.
Biomaterials and Tissue Engineering
Biomaterials and Tissue Engineering
The Allen Research group has interest in the development of biomaterials for applications such as musculoskeletal tissue engineering using ceramic polymer composite approaches, and vascular tissue engineering using elastomeric polymer scaffold development. Our work includes fabrication strategies including electrospinning.
DNA based Technologies
DNA based Technologies
The Allen lab is interested in the versatility of DNA. In our lab we utilize DNA for 1) cell signaling in the form of single stranded nucleic acid aptamers, 2) a functional crosslinking component for hydrogel technology, and 3) drug delivery strategies.
Current team members working in this area are:
Nikolaos Pipis - Zeyu Liu
Personalized cell and Biomaterial Engineering
Personalized cell and Biomaterial Engineering
We are leaders in the field advocating for the inclusion of sex and biological ancestry as biological variables in biomaterial and biomechanics studies. The Allen lab has worked to promote and demonstrate that cell-material interactions are influenced by these biological variables, and as we design new materials for broad biomedical applications it is critical that we consider the impact of patient specific factors in our material designs.
Microgravity and Space Biology
Microgravity and Space Biology
Our group is interested in how the space environment and particularly microgravity affects human health. We study vascular cells and tissues, blood flow hemodynamics, and the immune system under conditions of microgravity. Our group has a suite a bioreactor devices capable of exposing cells to simulated microgravity. In addition, our group has has an experiment flown aboard the International Space Station, on Space-X-17.
Current team members working in this area are:
Rachel Garner - Nikolaos Pipis
We are always looking for interested collaborators and students. Please reach out!
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